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With John Goh

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Lead Professional Officer

John Soo Yang
Goh

PhD in Biochemistry, National University of Singapore, Singapore
Email

Education

  • PhD in Biochemistry
    National University of Singapore , Singapore
  • Bachelor of Engineering in Chem
    National University of Singapore , Singapore

Technical Skills

  • Cell Line Engineering
  • Recombinant Protein Expression and Analysis
  • Molecular Diagnostics

Current Projects

  • An optimised workflow for a lab-developed Micro RnA based Liquid biopsy test kit for Lung Cancer Diagnosis
    – Present

Teaching Modules

Chemical Engineering, BEng (Hons)

  • CHE2015 - Engineering Practice

Pharmaceutical Engineering, BEng (Hons)

  • PHE3013 - Bioseparations Laboratory
  • PHE3018 - Unit Operations Laboratory
  • PHE3232 - Bioprocess Engineering
  • PHE3233 - Cell Culture Laboratory
  • PHE4012 - Plant Design and Operations
  • PHE2224 - Organic Chemistry Laboratory

Journal Papers

  • Goh JS, Chan KF, Song Z. Production of highly sialylated recombinant glycoproteins using ricinus communis agglutinin-I-resistant CHO Glycosylation Mutants. Methods Mol Biol. 2015. 1321, 323-33

  • Goh JS, Liu Y, Liu H, Chan KF, Wan C, Teo G, Zhou X, Xie F, Zhang P, Zhang Y, Song Z. Highly sialylated recombinant human erythropoietin production in large-scale perfusion bioreactor utilizing CHO-gmt4 (JW152) with restored GnT I function. Biotechnol J. 2014. 9, 100-9.

  • Goh JS, Liu Y, Chan KF, Wan C, Teo G, Zhang P, Zhang Y, Song Z. Producing recombinant therapeutic glycoproteins with enhanced sialylation using CHO-gmt4 glycosylation mutant cells. Bioengineered. 2014. 5, 269–73.

  • Zhang P, Haryadi R, Chan KF, Teo G, Goh J, Pereira NA, Feng H, Song Z. Identification of functional elements of the GDP-fucose transporter SLC35C1 using a novel Chinese hamster ovary mutant. Glycobiology. 2012. 22(7), 897-911.

  • Wong DC, Wong NS, Goh JS, May LM, Yap MG. Profiling of N-glycosylation gene expression in CHO cell fed-batch cultures. Biotechnol Bioeng. 2010. 15,107(3), 516-28.

  • Goh JS, Zhang P, Chan KF, Lee MM, Lim SF, Song Z. RCA-I-resistant CHO mutant cells have dysfunctional GnT I and expression of normal GnT I in these mutants enhances sialylation of recombinant erythropoietin. Metab Eng. 2010. 12, 360-8.