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Adjunct Associate Professor

Wai Chiong Loke

Health Living Lab, Innovation-as-a-Service
Institutional Review Board
Master of Business Administration, Anderson School of Management UCLA, National University of Singapore NUS, United States
Cluster:
Health and Social Sciences
Email
LinkedIn

Biography

Innovator and transformation leader, policymaker and educator, operator and investor.

My track record is that of clinician, administrator and business leader, including as Executive Director of National Medical Research Council (NMRC), Director of EDB-MOH Heath & Wellness/ Regional Health System, Cluster Group Director Quality/ Manpower (at different points of time) global health director and SEA partner at two Big4 Advisory firms, and long-time advisor and investor to businesses and startups.

My last assignment in public service was in Singapore's Ministry of Health Office for Healthcare Transformation (MOHT) 2019-2025, where I led the Integrated Health Promotion programme team to strategize and implement a comprehensive set of integrated initiatives and toolkits for Healthy Precincts, ultimately to scale nationwide. We collaborated with whole-of-government agencies (eg URA, HDB, BCA, NParks, PA, SGCares, SportSG, NCSS, GovTech, etc), weaving these into Healthier SG narrative. We also co-created Movements for Health (M4H), Design for Impact (D4I) and other community activation initiatives; and developed a national digital mental wellness solution platform called mindline.sg . I also led the MOHT Financing Redesign team to develop strategies and incentives at the system level to support population health care models, including national risk adjustment modeling within a capitation financing environment.

I serve on the board of Loving Heart Multi-Service Centre, help build the community in Yuhua (and Greater Jurong), and I am a District Councillor with South West CDC. I also sit on the advisory boards of several social enterprises, advise venture capital funds, and evaluate up-and-coming innovative startups on various granting and funding panels.

With my broad and varied career in public-private-people sectors, I bring to the table a rich experience spanning the entire healthcare value chain. I work with global investors, funders, governments, NGOs, hospitals and life sciences companies in a range of ways: innovate business models, enter new markets, strategize and execute M&A, raise growth capital; effect business transformation to future-proof companies; test-bed and deploy new technology or processes while managing day-to-day operations.

After decades of fruitful "connecting the dots" and co-designing strategies to "move the big dots" for health and communities, this next phase of portfolio work is about: building Platforms and Leverage; pursuing a Massive Transformative Purpose (MTP) and exponential impact; developing future-ready leaders and flourishing communities; solving the biggest problems at the intersection of health, social and community.

SIT Appointments

  • Health Living Lab, Innovation-as-a-Service
    – Present
  • Institutional Review Board
    – Present
  • Research Output Review Committee (RORC)
    –

Education

  • Fellow
    Academy of Medicine, Singapore , Singapore
  • Master of Business Administration
    Anderson School of Management UCLA, National University of Singapore NUS , United States
  • Fellowship of the College of Family Physicians Singapore
    College of Family Physicians Singapore , Singapore
  • Master of Medicine
    National University of Singapore , Singapore

Achievements

  • Public Service Commission - Governance & Leadership Programme (GLP 2010)
  • 39th Leadership Program on Japan 2010
  • MOH-SingHealth Health Manpower Development Plan HMDP Award 2004
  • NUS Medical Faculty Dean’s List Award 1995

Professional Certification

  • GRC Professional (Governance Risk Compliance)
    OCEG

Professional Memberships

  • Fellow of the Academy of Medicine Singapore (FAMS)
    – Present
  • Fellow of the College of Family Physicians Singapore (FCFPS)
    – Present

Corporate Experience

  • Global Advisor, Sugati Ventures
    Present
  • Senior Advisor, Vanden Advisory Services
    Present
  • Board Committee GRAD, Ronald McDonald House Charities
    Present
  • Advisory Panel, Asia Impact First Fund, OCTAVE Capital
    Present
  • Health Leaders Network, Urban Land Institute
    Present
  • Adjunct Professor, NUS Cities
    Present
  • Board Director, Vice President, Loving Heart MSC
    Present
  • Director (Integrated Health Promotion, Financing Redesign, mindline.sg), MOH Office for Healthcare Transformation (MOHT)
    –
  • Partner, Deloitte
    –
  • Investment Director, Sheares Healthcare (Temasek International)
    –
  • Director, Global Healthcare, KPMG
    –
  • Executive Director, National Medical Research Council, Singapore
    –
  • Director, Health & Wellness Programme Office, Economic Development Board
    –
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Current Projects

  • Healthy Cities / Built Environment-Health Related Research
    – Present

    Chua Alvin, Loke WC et al. Development of a Data Driven Activity Chain Modelling Methodology for Geodemographic Profiling of Singapore Residents and Analysis of Attitudes Towards Active Lifestyles ($1.3M, awarded by HPB in Aug 25) - Research commissioned by and jointly performed with HPB

    Chua Alvin, Loke WC et al. Living Lab to Assess the Feasibility and Costs to Sustain Enduring Datasets for Research & Education (funding under consideration with NRF, 2025)

    Aw Su, Loke WC et al. Impact of Co-Located Community Hubs on social capital and community capacities: Evaluation Framework and Development of Recommendations ($1.5M MND CoT Grant awarded Nov 2025)

    Aw Su, Wang Y, Poon KW, Loke WC. Purposeful Work in Later Life: Scaling Asset-Based Micro-Jobs for Active Ageing ($250K, MOE AcRF Tier 1 awarded Dec 2025)

    Aw Su, Loke WC et al. Generating Resilience and Wellbeing of Older Adults through Community-Centered and Empowerment Approaches (GRACE) ($250K, SPHSS grant awarded 2025)

    Yu Qian, Chiong YK, Falk MR, Loke WC et al. CUBS (Children’s Urban Behaviour & Spaces): Linking neighbourhood design, caregiver engagement, and children’s well-being in Singapore’s urban context through evidence, guidelines, and prototypes ($1.49M, MND CoT grant awarded March 2026)

Past Projects

  • Digital Mental Health Related (incl mindline.sg)
    –

    Weng JH, Hu Y, Heaukulani C, Tan C, Chang JK, Phang YS, Rajendram P, Tan WM, Loke WC, Morris RJT. Mental Wellness Self-Care in Singapore With mindline.sg: A Tutorial on the Development of a Digital Mental Health Platform for Behavior Change. J Med Internet Res 2024; 26:e44443

     Nur Atiqah Othman, …Wai Chiong Loke… Yinping Yang. Predicting public mental health needs in a crisis using social media indicators: a Singapore big data study. Nature Scientific Reports, 2024/10/05, 14/232222 

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Journal Papers

  • Loke WC, Tan HH, Lee H, K, Lau SM, Tay EG, Tan CB. Managing poorly controlled diabetes in the community: A step-up care model. 18th IDF Congress 2003. Abstract 1257. Diabetologia Supplement.

    Loke WC. Improving diabetes care in a polyclinic – a Clinical Practice Improvement Programme project. ministry of health Clinical Quality Improvement Month 2004, Singapore (abstract book – poster competition)

    Wild DM, Loke WC. Clinical practice improvement programme: Improving diabetes care in a polyclinic. SingHealth Scientific Meeting 2004, Singapore (Quality Highlights Feature).

    Heng J, Chia CM, Wild DM, Loke WC. Improving continuity of care by same physician for diabetic patients in a polyclinic. (Singapore Nursing Journal, July 2005)

    Lim SL, Tong CY, Ong KC, Loke WC, Lee EJC. Prevalence of malnutrition in a tertiary hospital. In: Oh VMS, Yap HK, editors. Proceedings of the National Healthcare Group Annual Scientific Congress; 10-11 Nov 2007: Singapore: Annals of the Academy of Medicine; 2007. p. S20.

    Wee HL, Loke WC, Li SC, Fong KY, Cheung YB, Machin D, Luo N, Thumboo J. Cross-cultural adaptation and validation of Singapore Malay and Tamil versions of the EQ-5D. Ann Acad Med Singapore 2007;36:403-8.

    Wee HL, Machin D, Loke WC, Li SC, Cheung YB, Luo N, Feeny D, Fong KY, Thumboo J. Assessing differences in utility scores: a comparison of four widely used preference-based instruments. Value Health. 2007 Jul-Aug;10(4):256-65. doi: 10.1111/j.1524-4733.2007.00174.x. PMID: 17645680.

    Wee HL, Cheung YB, Loke WC, Tan CB, Chow MH, LI SC, Fong KY, Feeny D, Machin D, Luo N, Thumboo J. Association of Body Mass Index with Health-Related Quality of Life: An Exploratory Study in a Multi-Ethnic Asian Population. Value in Health (Asian-Pacific Supplement 2007)

    Wee HL, Loke WC, Brazier J, Li SC, Cheung YB, Machin D, Luo N, Fong KY, Thumboo J. Cross Cultural Adaptation and Construct Validity of The Singapore English, Chinese, Malay and Tamil Versions of the SF-6D.

    WEE HL, LUO N, FEENY D, LI SC, LOKE WC, CHEUNG YB, MACHIN D, FONG KY, THUMBOO J. Cross-Cultural Adaptation and Construct Validity of the Singapore Chinese, Malay, and Tamil Versions of the Health Utilities Index Mark 2 and 3.

    Lim SL, Yu SM, Ee QY, Asim S, Chan YH, Loke WC. Nutrition Status and Hospitalisation Outcomes of Patients Receiving Tube Feeding in a Tertiary Hospital in Singapore. In: Oh VMS, Yap HK, editors. Proceedings of the National Healthcare Group Annual Scientific Congress; 16-17 Oct 2009: Singapore: Annals of the Academy of Medicine; 2009.

    Lim SL, Tong CY, Seet RCS, Loke WC, Ferguson M, Daniels L. Validation of Mid Arm Muscle Circumference and Triceps Skinfold Thickness with Subjective Global Assessment. In: Oh VMS, Yap HK, editors. Proceedings of the 8th Annual Scientific Congress National Healthcare Group; 16-17 Oct 2009: Singapore: Annals of the Academy of Medicine; 2009; 38:S8.

    Hwee-Lin Wee, Yin-Bu Cheung, David Machin, Wai-Chiong Loke, Kok-Yong Fong, Julian Thumboo, et al. Computerized and Interviewer Administration of Health-related Quality-of-Life Instruments Yield Clinically Equivalent Scores.

    Lim SL, Tong CY, Loke WC, Chen Y, Lee EJC, Daniels L, Ferguson M. Development and validation of 3-Minute Nutrition Screening (3-MinNS) Tool for acute hospital patients in Singapore. Asia Pacific Journal of Clinical Nutrition. 2009, 18(3).

    Lim SL, Ong KCB, Chan YH, Loke WC, Ferguson M, Daniels L. Malnutrition and its impact on cost of hospitalization, length of stay, readmission and 3-year mortality. Clinical Nutrition, 2012; 31(3):345-350. 

    Lim SL, Canavarro C, Zaw MH, Zhu F, Loke WC, Chan YH, Yeoh KG. Irregular Meal Timing is Associated with Helicobacter pylori Infection and Gastritis. International Scholarly Research Network–Nutrition. 2013.

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