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Assistant Professor

Rui Zhen TAN

Assistant Professor
Doctor of Philosophy, Biophysics , Harvard University, United States
Cluster:
Engineering
Email

SIT Appointments

  • Assistant Professor
    – Present

Education

  • Doctor of Philosophy, Biophysics
    Harvard University , United States
  • Bachelor of Applied and Engineering Physics
    Cornell University , United States

Achievements

  • A*STAR National Science Scholarship
  • Honorable Mention, International Physics Olympiad , Turkey

Research Interests

  • Mathematical modelling of biological systems
  • Bioinformatics
  • Systems Biology
  • Predictive maintenance

Journal Papers

  • Tan, R. Z., Markus, C., & Loh, T. P. (2020). Impact of delta check time intervals on error detection capability. Clinical Chemistry and Laboratory Medicine (CCLM), 58(3), 384-389.

  • Markus, C., Tan, R. Z. & Loh, T. P. (2020) Evidence-based approach to setting delta check rules, Critical Reviews in Clinical Laboratory Sciences, DOI: 10.1080/10408363.2020.1800585 

  • Tan, R. Z., Markus, C., & Loh, T. P. (2020). ANNALS EXPRESS: An approach to optimising delta checks in test panels–the effect of the number of rules included. Annals of Clinical Biochemistry, 0004563220904749.

  • Tan, R. Z., Markus, C., & Loh, T. P. (2020). Relationship between biological variation and delta check rules performance. Clinical Biochemistry.

  • Tan, R. Z., Loh, T. P., & Vasikaran, S. (2020). Bone turnover marker monitoring in osteoporosis treatment response. European Journal of Endocrinology, 1(aop).

  • Tan, R. Z., Punyalack, W., Graham, P., Badrick, T., & Loh, T. P. (2019). Detecting reagent lot shifts using proficiency testing data. Pathology, 51(7), 711-717.                                           

  • Tan, R. Z., Markus, C., Choy, K. W., Doery, J. C., & Loh, T. P. (2019). Optimized Delta Check Rules for Detecting Misidentified Specimens in Children. American Journal of Clinical Pathology.

  • Yip, A. K., Balachander, A., Tan, L. D., Liong, K. H., Tan, R. Z., Balabanian, K., ... & Chiam, K. H. (2019). A chemotaxis model to explain WHIM neutrophil accumulation in the bone marrow of WHIM mouse model. Blood Science, 1(1), 102-112.

  • Tan, R. Z., & Chiam, K. H. (2018). A computational model for how cells choose temporal or spatial sensing during chemotaxis. PLoS computational biology, 14(3), e1005966.

  • Tan, R. Z., Lai, T., & Chiam, K. H. (2017). The role of apical contractility in determining cell morphology in multilayered epithelial sheets and tubes. Physical Biology, 14(4).

  • Cheow, L. F., Courtois, E. T., Tan, Y., Viswanathan, R., Xing, Q., Tan, R. Z., Tan, Daniel S. W., Robson, P., Loh, Y.H., Stephen R Quake, S.R., & Burkholder, W. F. (2016). Single-cell multimodal profiling reveals cellular epigenetic heterogeneity. Nature Methods, 13, 833–836

  • Tan, R. Z., & Chiam, K. H. (2014). Combination of Chemotaxis and Differential Adhesion Leads to Robust Cell Sorting During Tissue Patterning. Biophysical Journal, 106(2), 173a.

  • Tan, R. Z., Ji, N., Mentink, R. A., Korswagen, H. C., & van Oudenaarden, A. (2013). Deconvolving the roles of Wnt ligands and receptors in sensing and amplification. Molecular systems biology, 9(1), 631.

  • Laksameethanasan, D., Tan, R. Z., Toh, G. W., & Loo, L. H. (2013). cellXpress: a fast and user-friendly software platform for profiling cellular phenotypes. BMC bioinformatics, 14(Suppl 16), S4.

  • Neuert, G., Munsky, B., Tan, R. Z., Teytelman, L., Khammash, M., & van Oudenaarden, A. (2013).Systematic identification of signal-activated stochastic gene regulation. Science, 339(6119), 584-587.

  • Tan, R. Z., & van Oudenaarden, A. (2010). Transcript counting in single cells reveals dynamics of rDNA transcription. Molecular systems biology, 6(1), 358.

  • Tan, R. Z., Agarwal, A., Balasubramanian, N., Kwong, D. L., Jiang, Y., Widjaja, E., & Garland, M. (2007).3D arrays of SERS substrate for ultrasensitive molecular detection. Sensors and Actuators A: Physical, 139(1), 36-41.

Conferences

  • Tan, R. Z., Wang, P. C., Lim, W. H., Ong, S. H. C., & Avnit, K. (2018, December). Early Prediction of Students' Mathematics Performance. In 2018 IEEE International Conference on Teaching, Assessment, and Learning for Engineering (TALE) (pp. 651-656). IEEE.

  • Biophysical Conference 2014
    Poster: Tan, R. Z., Yip, A.K., Chiam, K-H. Combination of chemotaxis and differential adhesion leads to robust cell sorting during tissue patterning

  • 5th q-bio Conference on Cellular Information Processing 2011
    Poster: Tan, R. Z., & van Oudenaarden, A. Different roles of Wnt ligands and receptors in regulating C.elegans' cell divisions (Selected for poster highlight)

  • Santa Cruz Developmental Biology Conference 2010
    Poster: Tan, R. Z., & van Oudenaarden, A. Role of Wnt and Notch Signaling in C.elegans' P cell development