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With Joy PANG

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Associate Professor

Joy PANG

Associate Professor
PhD (Biochemistry), University of Illinois, Urbana-Champaign, United States
Cluster:
Food, Chemical and Biotechnology
Email

SIT Appointments

  • Associate Professor
    – Present
  • Assistant Professor
    –
  • Lecturer
    –

Education

  • PhD (Biochemistry)
    University of Illinois, Urbana-Champaign , United States
  • BSc (Microbiology)
    University of California, San Diego , United States

Achievements

  • MITx Postdoctoral Teaching Fellow
    –
  • Howard Hughes Summer Research Fellow
    –

Corporate Experience

  • Research Associate, GenWay Biotech Inc, San Diego, CA, USA
    –

Research Interests

  • Protein chemistry
  • Synthetic biology
  • Bioanalytics
  • Genomics

Journal Papers

  • Keegan, C., Krutzik, S., Schenk, M., Scumpia, P. O., Lu, J., Pang, Y.L.J., Russell, B.S., Lim, K.S., Shell, S., Prestwich, E., Su, D., Elashoff, D., Hershberg, R.M., Bloom, B.R., Belisle, J.T., Fortune, S., Dedon, P.C., Pellegrini, M., and Modlin, R.L. (2018) Mycobacterium tuberculosis Transfer RNA Induces IL-12p70 via Synergistic Activation of Pattern Recognition Receptors within a Cell Network, Journal of Immunology, doi: 10.4049/jimmunol.1701733

  • Hia, F., Chionh, Y. H., Pang, Y. L. J., DeMott, M. S., McBee, M.E., and Dedon, P. C. (2015) High fidelity isolation of RNA from mycobacteria: A new approach optimized for quantitative and chemical analyses of non-coding RNA species, Nucleic acids research, 43, e32.

  • Cai, W. M., Chionh, Y. H., Hai, F., Gu, C., Kellner, S., McBee, M. E., Ng, C. S., Pang, Y. L. J., Prestwich, E. G., Lim, K. S., Indrakanti, R. B., Begley, T. J., Dedon, P. C. (2015) A platform for discovery and quantification of modified ribonucleosides in RNA: Application to stress-induced reprogramming of tRNA modifications. Methods enzymology, 560, 29-71

  • Hia, F., Chionh, Y. H., Pang, Y. L. J., DeMott, M. S., McBee, M.E., and Dedon, P. C. (2015) High fidelity isolation of RNA from mycobacteria: A new approach optimized for quantitative and chemical analyses of non-coding RNA species, Nucleic acids research, 43, e32.

  • Pang, Y. L. J., Abo, R., Levine, S. S., and Dedon, P. C. (2014) tRNA-seq for quantifying changes in tRNA copy number: Diverse cell stresses induce unique patterns of tRNA up- and down-regulation, Nucleic acids research, 42, e170.

  • Pang, Y. L. J., Poruri, K., and Martinis, S. A. (2014) tRNA synthetase – tRNA aminoacylation and beyond, Wiley Interdisciplinary Reviews. RNA, 5, 461-480.

  • Chionh, Y. H., Ho, C-H., Pruksakorn, D., Babu, R. I., Ng, C. S., Hia, F., McBee, M. E., Su, D., Pang, Y. L. J.,Gu, C., Dong, H., Prestwich, E., Shi, P-Y., Preiser, P., Alonso, S., and Dedon, P. C. (2013) A multidimensional platform for the purification of non-coding RNA species, Nucleic Acids Research, 41, e168.

  • Chan, C. T., Pang, Y. L. J., Deng, W., Babu, I. R., Dyavaiah, M., Begley, T. J., and Dedon, P. C. (2012) Reprogramming of tRNA modifications controls the oxidative stress response by codon-biased translation of proteins, Nat Commun 3, 937

  • Anderson, M., Huh, J.H., Ngo, T., Lee, A., Hernandez, G., Pang, Y. L. J., Perkins, J., Dutnall, R.N. (2010) Co-expression as a convenient method for the production and purification of core histones in bacteria, Protein Expr Purif 72(2), 194-204

  • Pang, Y. L. J. and Martinis, S. A. (2009) A paradigm shift for the amino acid editing mechanism of human cytoplasmic leucyl-tRNA synthetase, Biochemistry 48, 8958-64.

  • Nawaz, M. H., Pang, Y. L. J., and Martinis, S. A. (2007) Molecular and functional dissection of a putative RNA-binding region in yeast mitochondrial leucyl-tRNA synthetase, J Mol Biol 367, 384-394.

  • Martinis, S. A., and Pang, Y. L. J. (2007) Jekyll & Hyde: evolution of a superfamily, Chem Biol 14, 1307-1308.