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Associate Professor

Boon Seng WONG

Associate Professor
Doctor of Philosophy in Biology , Natural Environment Research Council & Open University, United Kingdom
Cluster:
Health and Social Sciences
Email
Google Scholar

SIT Appointments

  • Associate Professor
    – Present

Education

  • Doctor of Philosophy in Biology
    Natural Environment Research Council & Open University , United Kingdom
  • Master of Business Administration
    University of Manchester , United Kingdom
  • Bachelor of Science with Second Class Honours in Molecular Biology
    The Queen’s University of Belfast , United Kingdom

Achievements

  • Faculty Teaching Excellence Award (AY2013/2014), National University of Singapore, 2015
    –
  • Young Investigator Award, National University of Singapore, 2006
  • Medical Research Scientist Award, National Medical Research Council (NMRC), Singapore, 2001 to 2003
    –

Corporate Experience

  • Adjunct Associate Professor, Department of Physiology, National University of Singapore
  • Advisor, Research Office, National University Health System

Research Interests

  • Neurodevelopment and Ageing
  • Neural networking

Journal Papers

  • Zhu Y, Chai YL, Hilal S., Ikram MK, Venketasubramanian N, Wong BS, Chen CP and Lai MKP. (2017). Serum IL-8 is a marker of white matter hyperintensities in patients of Alzheimer’s disease. Alzheimers Dement (Amst). 7:41-47.

  • Suministrado SP, Wan EYS, Xu J, Teoh HL, Chan BPL, Venketasubramanian N, Seet RCS, Chen CLH, Wong BS, Sharma VK and Dong YH. (2017). Post-stroke cognition decline is independent of longitudinal changes in cerebral hemodynamics parameters. J Neuroimaging. 27(3):326-332.

  • Yang L, Gao Z, Hu L, Wu G, Yang X, Zhang L, Zhu Y, Wong BS, Xin W and Li C. (2016). GPI anchor modification machinery deficiency is responsible for the formation of Pro-PrP in BxPC-3 and increases cancer cell motility. J Biol Chem 291(8):3905-3917.

  • Too IHK, Yeo H, Yan B, Libau EA, Howe J, Lim Z, Suku-Maran S, Ong WY, Chua KB, Wong BS, Chow VTK and Alonso S. (2016). Enterovirus 71 infection of motor neuron-like NSC-34 cells undergoes a non-lytic exit pathway. Sci Rep 6:36983.

  • Chai YL, Yeo HK, Wang J, Hilal S, Ikram MK, Venketasubramanian N, Wong BSand Chen CL. (2016). Apolipoprotein E4 is not associated with vascular cognitive impairment. J Alzheimer Dis 51(4):1111-1118.

  • Chan ES, Shetty MS, Sajikumar S, Chen CL, Soong TW and Wong BS. (2016). ApoE4 expression accelerates hippocampus-dependent cognitive deficits by enhancing Aβ impairment of insulin signaling in an Alzheimer’s Disease mouse model. Sci Rep 6:26119.

  • Chan EC, Chen C, Cole GM and Wong BS. (2015). Differential interaction of apolipoprotein E isoforms with insulin receptors modulates insulin signaling in mutant human amyloid precursor protein transgenic mice. Sci Rep 5:13842.

  • Yong SM, Ong QR, Siew BE and Wong BS. (2014). The effect of chicken extract on ERK/CREB signaling is ApoE isoform-dependent. Food Func 5(9):2043-2051.

  • Ong QR, Chan ES, Lim ML, Cole GM and Wong B-S. (2014). Reduced phosphorylation of brain insulin receptor substrate and Akt proteins in apolipoprotein-E4 targeted replacement mice. Sci Rep 4:3754.

  • Goh DA, Dong YH, Lee WY, Koay WI, Tay SZ, Soon D, Chen C, Brittain CF, Lowe SL and Wong B-S. (2014). A pilot study to examine the correlation between cognition and biochemical biomarkers in a Singapore Chinese male cohort with type 2 diabetes mellitus. PLOS One 9:e96874.

  • Yong SM, Lim ML, Low CM and Wong BS. (2014). Reduced neuronal signaling in the ageing apolipoprotein-E4 targeted replacement female mice. Sci Rep4:6580.

  • Ong QR, Chan ES, Lim ML and Wong B-S. (2014). Expressing human apolipoprotein E4 reduces insulin-receptor substrate 1 expression and Akt phosphorylation in the ageing liver. FEBS OpenBio 4:260-265.