Boon Seng WONG
- Associate Professor– Present
- Doctor of Philosophy in BiologyNatural Environment Research Council & Open University , United Kingdom
- Master of Business AdministrationUniversity of Manchester , United Kingdom
- Bachelor of Science with Second Class Honours in Molecular BiologyThe Queen’s University of Belfast , United Kingdom
- Faculty Teaching Excellence Award (AY2013/2014), National University of Singapore, 2015–
- Young Investigator Award, National University of Singapore, 2006
- Medical Research Scientist Award, National Medical Research Council (NMRC), Singapore, 2001 to 2003–
- Advisor, Research Office, National University Health System
- Adjunct Associate Professor, Department of Physiology, National University of Singapore
Neurodevelopment and Ageing
Zhu Y, Chai YL, Hilal S., Ikram MK, Venketasubramanian N, Wong BS, Chen CP and Lai MKP. (2017). Serum IL-8 is a marker of white matter hyperintensities in patients of Alzheimer’s disease. Alzheimers Dement (Amst). 7:41-47.
Suministrado SP, Wan EYS, Xu J, Teoh HL, Chan BPL, Venketasubramanian N, Seet RCS, Chen CLH, Wong BS, Sharma VK and Dong YH. (2017). Post-stroke cognition decline is independent of longitudinal changes in cerebral hemodynamics parameters. J Neuroimaging. 27(3):326-332.
Chan ES, Shetty MS, Sajikumar S, Chen CL, Soong TW and Wong BS. (2016). ApoE4 expression accelerates hippocampus-dependent cognitive deficits by enhancing Aβ impairment of insulin signaling in an Alzheimer’s Disease mouse model. Sci Rep 6:26119.
Yang L, Gao Z, Hu L, Wu G, Yang X, Zhang L, Zhu Y, Wong BS, Xin W and Li C. (2016). GPI anchor modification machinery deficiency is responsible for the formation of Pro-PrP in BxPC-3 and increases cancer cell motility. J Biol Chem 291(8):3905-3917.
Too IHK, Yeo H, Yan B, Libau EA, Howe J, Lim Z, Suku-Maran S, Ong WY, Chua KB, Wong BS, Chow VTK and Alonso S. (2016). Enterovirus 71 infection of motor neuron-like NSC-34 cells undergoes a non-lytic exit pathway. Sci Rep 6:36983.
Chai YL, Yeo HK, Wang J, Hilal S, Ikram MK, Venketasubramanian N, Wong BSand Chen CL. (2016). Apolipoprotein E4 is not associated with vascular cognitive impairment. J Alzheimer Dis 51(4):1111-1118.
Chan EC, Chen C, Cole GM and Wong BS. (2015). Differential interaction of apolipoprotein E isoforms with insulin receptors modulates insulin signaling in mutant human amyloid precursor protein transgenic mice. Sci Rep 5:13842.
Yong SM, Lim ML, Low CM and Wong BS. (2014). Reduced neuronal signaling in the ageing apolipoprotein-E4 targeted replacement female mice. Sci Rep4:6580.
Ong QR, Chan ES, Lim ML and Wong B-S. (2014). Expressing human apolipoprotein E4 reduces insulin-receptor substrate 1 expression and Akt phosphorylation in the ageing liver. FEBS OpenBio 4:260-265.
Yong SM, Ong QR, Siew BE and Wong BS. (2014). The effect of chicken extract on ERK/CREB signaling is ApoE isoform-dependent. Food Func 5(9):2043-2051.
Ong QR, Chan ES, Lim ML, Cole GM and Wong B-S. (2014). Reduced phosphorylation of brain insulin receptor substrate and Akt proteins in apolipoprotein-E4 targeted replacement mice. Sci Rep 4:3754.
Goh DA, Dong YH, Lee WY, Koay WI, Tay SZ, Soon D, Chen C, Brittain CF, Lowe SL and Wong B-S. (2014). A pilot study to examine the correlation between cognition and biochemical biomarkers in a Singapore Chinese male cohort with type 2 diabetes mellitus. PLOS One 9:e96874.